Educational reference, not medical advice. Talk to a clinician before changing what you take.Read more.

Condition

Migraine

A neurological disorder of recurrent, often one-sided throbbing headaches, sometimes with aura, nausea, and light sensitivity.

See a clinician

Some causes of migraine need medical care, not self-treatment. Seek help for any of these:

  • A sudden "thunderclap" headache that peaks within a minute
  • The "worst headache of your life", or a clearly different new pattern
  • Headache with fever and a stiff neck, confusion, weakness, or vision loss
  • A new headache after age 50, or with a history of cancer or weakened immunity
  • Headache after head injury, or that wakes you from sleep

What may help

Remedies studied for migraine, ranked by strength of evidence.

  • B
    Butterbur herb

    A PA-free extract (75 mg twice daily) cut migraine frequency about 48% vs 26% placebo — but safety concerns dominate the decision.

  • B
    Coenzyme Q10 supplement

    About 300 mg/day modestly reduced migraine frequency and days, and was well tolerated.

  • B
    Magnesium nutrient

    About 600 mg/day modestly reduces migraine attack frequency; evidence is mixed but supportive.

  • B
    Riboflavin (vitamin B2) nutrient

    High-dose riboflavin (400 mg/day) reduced migraine frequency with a low number-needed-to-treat.

  • C
    Feverfew herb

    May modestly reduce migraine attack frequency, but trials are inconsistent and low-quality.

Several supplements have genuine preventive evidence for migraine — magnesium, riboflavin, and CoQ10 are well tolerated; feverfew is weaker; butterbur works but carries a liver-toxicity concern unless PA-free. These reduce attack frequency; they are not acute pain relief.