Remedy · supplement
Glucosamine sulfate
Also: glucosamine
A cartilage building-block supplement whose benefit appears to depend heavily on the exact preparation.
Evidence by condition
Each grade reflects the research for Glucosamine sulfate and that condition specifically.
- CKnee osteoarthritis
Mixed and brand-dependent: patented crystalline glucosamine sulfate may modestly help pain and function, but other preparations show no clear benefit over placebo.
2 citation s
- Glucosamine therapy for treating osteoarthritis Systematic review 2005 · n=4,963 · Cochrane Database of Systematic Reviews · DOI 10.1002/14651858.CD002946.pub2
- Glucosamine and Chondroitin for Osteoarthritis: What You Need To Know NCCIH · accessed 2026-06-21
- Glucosamine therapy for treating osteoarthritis
- DHip osteoarthritis
The dedicated hip trial found no benefit over placebo — glucosamine's (disputed) positive data are knee-only.
2 citation s
- Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial Randomized trial 2008 · n=222 · Annals of Internal Medicine · PMID 18283204 · DOI 10.7326/0003-4819-148-4-200802190-00005
- Glucosamine and Chondroitin for Osteoarthritis: What You Need To Know NCCIH · accessed 2026-06-21
- Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial