Remedy · supplement
Glycine
Also: glycine amino acid
An amino acid that may modestly improve sleep when taken before bed.
Evidence by condition
Each grade reflects the research for Glycine and that condition specifically.
- CInsomnia
A small crossover study found 3 g before bed improved subjective sleep quality and shortened time to fall asleep on polysomnography; evidence rests on a few small studies.
1 citation
- Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes Randomized trial 2007 · Sleep and Biological Rhythms · DOI 10.1111/j.1479-8425.2007.00262.x
- Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes
Glycine is an inhibitory neurotransmitter that may help sleep onset, possibly by gently lowering core body temperature. The evidence is preliminary — a few small trials — but it is inexpensive and well tolerated.