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Research · Randomized controlled trial

Effect of Alpha-Lipoic Acid on Clinical and Neurophysiologic Recovery of Carpal Tunnel Syndrome: A Double-Blind, Randomized Clinical Trial

What it found

ALA around surgery improved clinical and neurophysiologic recovery versus placebo — but the trial enrolled only 20 people.

Design
Randomized controlled trial
Year
2018
Sample size
20
Population
adults with carpal tunnel syndrome undergoing surgical decompression (very small)
Intervention
ALA 600 mg/day for 1 month pre-op and 2 months post-op vs placebo
Outcome
Boston Questionnaire, clinical signs, nerve conduction
Journal
Journal of Medicinal Food

Citation last checked 2026-06-21.