Research · Meta-analysis
Effects of berberine on blood glucose in patients with type 2 diabetes mellitus: a systematic literature review and a meta-analysis
What it found
Lowered fasting glucose by ~0.54 mmol/L and HbA1c by ~0.54; the effect attenuated beyond 90 days, above 2 g/day, and in people over 60.
- Design
- Meta-analysis
- Year
- 2019
- Sample size
- 2,313
- Population
- adults with type 2 diabetes (28 RCTs)
- Intervention
- berberine vs control, often added to hypoglycemic agents
- Outcome
- fasting glucose, postprandial glucose, HbA1c
- Journal
- Endocrine Journal
Citation last checked 2026-06-21.