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Research · Meta-analysis

Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis

What it found

Lowered fasting glucose by ~0.82 mmol/L, HbA1c by ~0.63 percentage points, and 2-hour postprandial glucose by ~1.16 mmol/L, without a significant rise in adverse events or hypoglycemia.

Design
Meta-analysis
Year
2022
Sample size
3,048
Population
adults with type 2 diabetes (37 studies)
Intervention
berberine, alone or added to oral hypoglycemic agents
Outcome
fasting glucose, HbA1c, 2-hour postprandial glucose
Journal
Frontiers in Pharmacology

Citation last checked 2026-06-21.