Research · Meta-analysis
Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis
What it found
In community-dwelling older adults, calcium + vitamin D was NOT associated with lower hip fracture risk (RR 1.09) or total fractures — the benefit seen in care-home populations did not carry over.
- Design
- Meta-analysis
- Year
- 2017
- Sample size
- 51,145
- Population
- community-dwelling adults older than 50 (33 RCTs)
- Intervention
- calcium, vitamin D, or combined supplements vs placebo / no treatment
- Outcome
- incident hip and total fractures
- Journal
- JAMA
Citation last checked 2026-06-21.