Research · Meta-analysis
The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis
What it found
A large pooled benefit over placebo (Hedges g ≈ −1.21), but the authors cautioned this is likely overstated by high risk of bias and publication bias.
- Design
- Meta-analysis
- Year
- 2017
- Population
- women with PMS (14 RCTs pooled)
- Intervention
- standardized Vitex agnus-castus (chasteberry) extracts vs placebo or comparators
- Outcome
- PMS symptom score
- Journal
- American Journal of Obstetrics and Gynecology
Citation last checked 2026-06-21.