Research · Randomized controlled trial
High versus low dosing of oral colchicine for early acute gout flare (AGREE trial)
What it found
Low-dose colchicine matched high-dose efficacy with an adverse-event rate like placebo.
- Design
- Randomized controlled trial
- Year
- 2010
- Sample size
- 184
- Population
- adults with an acute gout flare
- Intervention
- low-dose vs high-dose colchicine
- Outcome
- pain at 24 h
- Journal
- Arthritis & Rheumatism
Citation last checked 2026-06-21.