Research · Randomized controlled trial
Ginkgo biloba for prevention of dementia: a randomized controlled trial (Ginkgo Evaluation of Memory study)
What it found
Ginkgo did NOT reduce dementia (HR 1.12) or Alzheimer disease (HR 1.16) — if anything slightly the wrong direction; no benefit for prevention.
- Design
- Randomized controlled trial
- Year
- 2008
- Sample size
- 3,069
- Population
- community-dwelling adults aged 72–96, normal cognition or mild cognitive impairment; median 6.1-year follow-up
- Intervention
- Ginkgo biloba extract (EGb 761) 120 mg twice daily vs placebo
- Outcome
- incident all-cause dementia and Alzheimer disease
- Journal
- JAMA
Citation last checked 2026-06-21.