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Research · Randomized controlled trial

Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes

What it found

Glycine improved subjective sleep quality and shortened polysomnographic latency to sleep onset and to slow-wave sleep, without changing overall sleep architecture; a small early study.

Design
Randomized controlled trial
Year
2007
Population
adult volunteers with continuously unsatisfactory sleep (small crossover)
Intervention
glycine 3 g before bedtime vs placebo
Outcome
subjective sleep quality and polysomnography
Journal
Sleep and Biological Rhythms

Citation last checked 2026-06-21.