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Research · Randomized controlled trial

Total triterpenic fraction of Centella asiatica in the treatment of venous hypertension: a randomized trial using a combined microcirculatory model

What it found

Both doses significantly improved microcirculation and symptom scores versus placebo (no change in placebo), with the larger effect at 120 mg/day.

Design
Randomized controlled trial
Year
2001
Sample size
99
Population
patients with venous hypertensive microangiopathy
Intervention
Centella asiatica triterpenic fraction 60 or 120 mg/day vs placebo, 8 weeks
Outcome
laser Doppler flowmetry, transcutaneous gas measures, symptom scores
Journal
Angiology

Citation last checked 2026-06-21.