Research · Meta-analysis
Effects of oral administration of β-hydroxy β-methylbutyrate on lean body mass in older adults: a systematic review and meta-analysis
What it found
HMB alone modestly increased fat-free mass (effect size ~0.59), but added no measurable benefit on top of an exercise program.
- Design
- Meta-analysis
- Year
- 2021
- Sample size
- 448
- Population
- older adults (9 RCTs)
- Intervention
- oral HMB, with or without exercise, vs control
- Outcome
- lean / fat-free body mass
- Journal
- European Geriatric Medicine
Citation last checked 2026-06-21.