Research · Randomized controlled trial
Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis
What it found
Lower symptom scores at day 2 and faster resolution versus placebo, especially when started early; small trial of one proprietary extract.
- Design
- Randomized controlled trial
- Year
- 1999
- Sample size
- 66
- Population
- patients with recurrent cold sores (≥4 episodes/year)
- Intervention
- 1% standardized lemon balm (Melissa officinalis) cream applied 4×/day for 5 days vs placebo
- Outcome
- combined symptom score; healing
- Journal
- Phytomedicine
Citation last checked 2026-06-21.