Research · Randomized controlled trial
The effects of Melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial
What it found
Anxiety and depression improved significantly more with lemon balm than placebo over 12 weeks.
- Design
- Randomized controlled trial
- Year
- 2023
- Sample size
- 60
- Population
- type 2 diabetes patients aged 20–65 with depressive symptoms (44 completed)
- Intervention
- 700 mg/day Melissa officinalis extract vs placebo for 12 weeks
- Outcome
- anxiety and depression scores (Beck inventories)
- Journal
- BMC Complementary Medicine and Therapies
Citation last checked 2026-06-21.