Research · Randomized controlled trial
Success of L-lysine therapy in frequently recurrent herpes simplex infection: treatment and prophylaxis
What it found
Reported fewer and milder recurrences with lysine versus placebo — but other trials found no effect, so the overall evidence is conflicting.
- Design
- Randomized controlled trial
- Year
- 1987
- Sample size
- 52
- Population
- adults with frequently recurrent herpes simplex
- Intervention
- oral L-lysine 1,000 mg three times daily for 6 months vs placebo
- Outcome
- recurrence frequency, severity, healing time
- Journal
- Dermatologica
Citation last checked 2026-06-21.