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Research · Randomized controlled trial

Short-term magnesium therapy alleviates moderate stress in patients with fibromyalgia: a randomized double-blind clinical trial

What it found

Missed its primary stress endpoint overall; pain severity fell significantly versus placebo and stress improved in a subgroup — weak, mixed evidence.

Design
Randomized controlled trial
Year
2022
Sample size
75
Population
patients with fibromyalgia
Intervention
magnesium chloride 100 mg/day for 1 month vs placebo
Outcome
stress (DASS-42, primary), pain
Journal
Nutrients

Citation last checked 2026-06-21.