Research · Randomized controlled trial
Oral magnesium successfully relieves premenstrual mood changes
What it found
Magnesium reduced the total symptom score and the negative-affect (mood) cluster versus placebo; a small early trial.
- Design
- Randomized controlled trial
- Year
- 1991
- Sample size
- 32
- Population
- women with premenstrual syndrome
- Intervention
- magnesium (360 mg elemental) three times daily from mid-cycle to menses, 2 cycles, vs placebo
- Outcome
- premenstrual mood / symptom scores
- Journal
- Obstetrics & Gynecology
Citation last checked 2026-06-21.