Research · Study
Magnesium citrate monotherapy improves restless legs syndrome symptoms: an open-label pilot study
What it found
Reduced IRLS scores in an open-label pilot, but with no placebo control; the authors called for a randomized placebo-controlled trial. Weak evidence.
- Design
- Study
- Year
- 2024
- Sample size
- 12
- Population
- treatment-naive adults with primary restless legs syndrome
- Intervention
- magnesium citrate 200 mg/day for 8 weeks (open-label, uncontrolled)
- Outcome
- RLS severity (IRLS), quality of life
- Journal
- Journal of Clinical Sleep Medicine
Citation last checked 2026-06-21.