Research · Randomized controlled trial
Efficacy of Supportive Therapy of Allergic Rhinitis by Stinging Nettle (Urtica dioica) root extract: a Randomized, Double-Blind, Placebo-Controlled, Clinical Trial
What it found
Both nettle and placebo improved symptoms similarly on SNOT-22 — no symptom advantage for nettle; high dropout limits the trial.
- Design
- Randomized controlled trial
- Year
- 2017
- Sample size
- 74
- Population
- patients with allergic rhinitis and a positive skin-prick test (only 40 completed)
- Intervention
- Urtica dioica root extract 150 mg four times daily for 1 month vs placebo
- Outcome
- SNOT-22 symptom severity, nasal eosinophils, cytokines
- Journal
- Iranian Journal of Pharmaceutical Research
Citation last checked 2026-06-21.