Research · Randomized controlled trial
Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris
What it found
Both gels reduced acne grade comparably by week 8; nicotinamide worked better on oily skin, clindamycin on non-oily skin.
- Design
- Randomized controlled trial
- Year
- 2013
- Sample size
- 80
- Population
- patients with moderate inflammatory facial acne (40 per arm)
- Intervention
- topical 4% nicotinamide gel vs 1% clindamycin gel, twice daily for 8 weeks
- Outcome
- acne grade/severity; effect by skin type
- Journal
- International Journal of Dermatology
Citation last checked 2026-06-21.