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Research · Systematic review

Probiotics for preventing acute upper respiratory tract infections

What it found

Probiotics reduced the proportion of people with at least one acute URTI (RR 0.76) and cut antibiotic use and mean episode duration (~1 day) — though most estimates are low-to-moderate certainty and no formulation can be recommended.

Design
Systematic review
Year
2022
Sample size
6,950
Population
children, adults, and older adults (23 RCTs analyzed)
Intervention
various probiotic strains (mostly Lactobacillus/Bifidobacterium) vs placebo
Outcome
acute URTI episodes, episode duration, antibiotic use
Journal
Cochrane Database of Systematic Reviews

Citation last checked 2026-06-21.