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Research · Systematic review

S-Adenosylmethionine for osteoarthritis of the knee or hip

What it found

Inconclusive — a possible benefit on pain and function, but the evidence is too low-quality to recommend routine use.

Design
Systematic review
Year
2009
Sample size
656
Population
adults with knee or hip OA
Intervention
SAMe
Outcome
pain, function
Journal
Cochrane Database of Systematic Reviews

Citation last checked 2026-06-21.