Research · Randomized controlled trial
The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study
What it found
Tea tree oil gel was ~3.6× more effective than placebo for total lesion count and ~5.8× for acne severity, with similar, tolerable side effects.
- Design
- Randomized controlled trial
- Year
- 2007
- Sample size
- 60
- Population
- patients with mild-to-moderate acne vulgaris (30 tea tree oil, 30 placebo)
- Intervention
- 5% topical tea tree oil gel twice daily
- Outcome
- total lesion count and acne severity index
- Journal
- Indian Journal of Dermatology, Venereology and Leprology
Citation last checked 2026-06-21.