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Research · Meta-analysis

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data

What it found

Vitamin D modestly reduced the odds of at least one acute respiratory infection (aOR 0.88), with a much larger benefit in severely deficient people (aOR 0.58) and only for daily/weekly — not bolus — dosing.

Design
Meta-analysis
Year
2017
Sample size
10,933
Population
participants of all ages across 25 RCTs
Intervention
vitamin D (daily, weekly, or bolus) vs placebo
Outcome
incidence of acute respiratory tract infection
Journal
BMJ

Citation last checked 2026-06-21.