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Research · Randomized controlled trial

The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults: A Response-Adaptive, Randomized Clinical Trial (STURDY)

What it found

Higher-dose vitamin D did not prevent falls; 2000 and 4000 IU/day had higher fall/death rates than 1000 IU/day — suggesting no benefit and possible harm at higher doses.

Design
Randomized controlled trial
Year
2021
Sample size
688
Population
community-dwelling adults aged ≥70 at elevated fall risk
Intervention
vitamin D3 200 (control), 1000, 2000, or 4000 IU/day
Outcome
time to first fall or death
Journal
Annals of Internal Medicine

Citation last checked 2026-06-21.