Research · Meta-analysis
Does vitamin D supplementation impact fibromyalgia-related pain? A systematic review and meta-analysis
What it found
Reported a modest, significant pain reduction (SMD ≈ −0.85), strongest in deficient patients; a separate meta-analysis found the VAS effect non-significant, so certainty is low-to-moderate.
- Design
- Meta-analysis
- Year
- 2025
- Sample size
- 310
- Population
- adults with fibromyalgia (5 RCTs)
- Intervention
- vitamin D supplementation vs control
- Outcome
- fibromyalgia-related pain (NRS/VAS, FIQ)
- Journal
- Nutrients
Citation last checked 2026-06-21.