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Research · Meta-analysis

The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis

What it found

Pyridoxine significantly improved pregnancy nausea on both the Rhodes and PUQE scores; effect on vomiting frequency was weaker and less consistent.

Design
Meta-analysis
Year
2023
Population
pregnant women with nausea and vomiting of pregnancy (18 studies)
Intervention
pyridoxine alone or combined with an active ingredient vs comparator
Outcome
nausea/vomiting severity (Rhodes and PUQE scores)
Journal
Archives of Gynecology and Obstetrics

Citation last checked 2026-06-21.