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Research · Meta-analysis

Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials

What it found

Collagen reduced knee OA pain (MD −13.63) and improved function vs placebo.

Design
Meta-analysis
Year
2025
Sample size
870
Population
adults with knee OA
Intervention
oral collagen peptides
Outcome
pain, function
Journal
Clinical and Experimental Rheumatology

Citation last checked 2026-06-21.