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Research · Randomized controlled trial

Prophylaxis of migraine with oral magnesium: a prospective, multi-center, placebo-controlled, double-blind randomized study

What it found

Cut attack frequency 41.6% vs 15.8% placebo (a separate trial was negative — evidence is mixed).

Design
Randomized controlled trial
Year
1996
Sample size
81
Population
adults with migraine
Intervention
oral magnesium 600 mg/day
Outcome
attack frequency
Journal
Cephalalgia

Citation last checked 2026-06-21.