Research · Randomized controlled trial
Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomized controlled trial
What it found
59% were ≥50% responders vs 15% placebo (number-needed-to-treat 2.3).
- Design
- Randomized controlled trial
- Year
- 1998
- Sample size
- 55
- Population
- adults with migraine
- Intervention
- riboflavin 400 mg/day
- Outcome
- attack frequency
- Journal
- Neurology
Citation last checked 2026-06-21.